Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Nov;32(11):819-28.
doi: 10.1038/jp.2012.90. Epub 2012 Jul 12.

Developmental and behavioral consequences of prenatal cocaine exposure: a review

Affiliations
Review

Developmental and behavioral consequences of prenatal cocaine exposure: a review

B L Lambert et al. J Perinatol. 2012 Nov.

Abstract

Substance use among pregnant women continues to be a major public health concern, posing potential risk to their drug-exposed children as well as burdens on society. This review is intended to discuss the most recent literature regarding the association between in utero cocaine exposure and developmental and behavioral outcomes from birth through adolescence across various domains of functioning (growth, neurobiology, intelligence, academic achievement, language, executive functioning, behavioral regulation and psychopathology). In addition, methodological limitations, associated biological, sociodemographic and environmental risk factors and future directions in this area of research are discussed. Given the large number of exposed children in the child welfare system and the increased need for medical, mental health and special education services within this population, more definitively documenting associations between prenatal cocaine exposure and later child outcomes is essential in order to be able to prospectively address the many significant public health, economic and public policy implications.

PubMed Disclaimer

Conflict of interest statement

Conflict of interest

The authors declare no conflict of interest.

References

    1. Substance Abuse and Mental Health Services Administration. NSDUH Series H-36, HHS Publication No SMA 09-4434) Rockville, MD: 2009. Results from the 2008 National Survey on Drug Use and Health: National Findings (Office of Applied Studies.
    1. Wenzel SL. Prenatal Cocaine Exposure: Scientific Considerations and Policy Implications. RAND Drug Policy Research Center; Santa Monica, CA: 2001.
    1. Chasnoff IJ, Anson A, Hatcher R, Stenson H, Iaukea K, Randolph LA. Prenatal exposure to cocaine and other drugs: outcome at four to six years. Ann NY Acad Sci. 1998;846:314–328. - PubMed
    1. Ventura SJ, Abma JC, Mosher WD, Henshaw SK. Estimated pregnancy rates for the United States, 1990–2004. Natl Vital Stat Rep. 2008;56(15):1–25. 28. - PubMed
    1. Everitt BJ, Robbins TW. Neural systems of reinforcement for drug addiction: from actions to habits to compulsions. Nat Neurosci. 2005;8(11):1481–1489. - PubMed

Publication types