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Comparative Study
. 1979 Jul;10(1):111-3.
doi: 10.1128/jcm.10.1.111-113.1979.

Effect of enzymes on rotavirus infectivity

B B Barnett, R S Spendlove, M L Clark
Comparative Study

Effect of enzymes on rotavirus infectivity

B B Barnett et al. J Clin Microbiol. 1979 Jul.

Abstract

The infectivity of a bovine rotavirus was enhanced 140-, 8-, and 3-fold, respectively, by trypsin, protease, and lactase. Ficin, carboxypeptidases A and B, lysozyme, and beta-galactosidase had little effect on the infectivity. Chymotrypsin caused a threefold decrease in the infectivity. Trypsin acts directly on the rotavirus and not on the host cell.

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References

    1. J Bacteriol. 1965 Mar;89:597-602 - PubMed
    1. J Gen Virol. 1977 Sep;36(3):395-402 - PubMed
    1. J Clin Microbiol. 1979 Mar;9(3):413-7 - PubMed
    1. J Gen Virol. 1978 Jul;40(1):213-8 - PubMed
    1. J Clin Microbiol. 1977 Dec;6(6):610-7 - PubMed

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