"Human guinea pigs"--a history
- PMID: 2279175
- PMCID: PMC1679859
- DOI: 10.1136/bmj.301.6766.1456
"Human guinea pigs"--a history
Abstract
KIE: In 1967, Pappworth expanded a 1962 journal article on unethical experiments with human subjects into a book, Human Guinea Pigs: Experimentation on Man (Routledge). Here Pappworth describes the impetus behind his controversial article and book, and the reaction to both from the British media, the British medical establishment, the Ministry of Health, and Parliament. He discusses the effectiveness of ethical codes, editorial policies, and research ethics committees in safeguarding human subjects from overzealous or unethical researchers. He warns of the need for all those involved in human experimentation -- researchers, their units, ethics committees, editors of medical journals -- to tighten the self regulatory mechanisms in place lest public reaction to unethical research bring on legal sanctions.
Comment in
-
Human guinea pigs.BMJ. 1991 Feb 16;302(6773):411. BMJ. 1991. PMID: 2004153 Free PMC article. No abstract available.
Similar articles
-
Ethical considerations in human experimentation.J Clin Pharmacol New Drugs. 1975 Aug-Sep;15(8-9):579-90. J Clin Pharmacol New Drugs. 1975. PMID: 11661224 No abstract available.
-
Trends in the social control of medical and psychiatric research.Law Ment Health. 1988;4:1-47. Law Ment Health. 1988. PMID: 11655151 Review. No abstract available.
-
Criteria for decision making in local research (ethics) committees.Public Health. 1993 Nov;107(6):403-11. doi: 10.1016/s0033-3506(05)80165-9. Public Health. 1993. PMID: 8290685 Review.
-
Government guinea pigs.N Y Times Web. 1994 Jan 9:E21. N Y Times Web. 1994. PMID: 11646304 No abstract available.
-
The regulation of human experimentation in the United States--a personal odyssey.IRB. 1987 Jan-Feb;9(1):1-6. IRB. 1987. PMID: 11649890 No abstract available.
Cited by
-
Human guinea pigs.BMJ. 1991 Feb 16;302(6773):411. BMJ. 1991. PMID: 2004153 Free PMC article. No abstract available.
-
Ethical Challenges in Infant Feeding Research.Nutrients. 2017 Jan 11;9(1):59. doi: 10.3390/nu9010059. Nutrients. 2017. PMID: 28085057 Free PMC article. Review.
-
Protecting the public from the adverse effects of confused research ethics.J R Soc Med. 2021 Nov;114(11):507-512. doi: 10.1177/01410768211051720. Epub 2021 Oct 26. J R Soc Med. 2021. PMID: 34698579 Free PMC article. No abstract available.
-
Assembling comparison groups to assess the effects of health care.J R Soc Med. 1997 Jul;90(7):379-86. doi: 10.1177/014107689709000706. J R Soc Med. 1997. PMID: 9290419 Free PMC article. Review. No abstract available.
-
Biomedical research ethics in Cameroon: a survey to assess training needs of medical residents and students.BMC Med Educ. 2019 Jan 3;19(1):5. doi: 10.1186/s12909-018-1431-8. BMC Med Educ. 2019. PMID: 30606193 Free PMC article.
References
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources