Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012:2012:249705.
doi: 10.1155/2012/249705. Epub 2012 Jun 26.

Chronic q Fever with no elevation of inflammatory markers: a case report

Matteo Boattini  1 , André Almeida, Rita Barata Moura, João Abreu, Ana Sofia Santos, Miguel Toscano Rico
Affiliations

Chronic q Fever with no elevation of inflammatory markers: a case report

Matteo Boattini et al. Case Rep Med. 2012.

Abstract

We describe the case of a 55-year-old man with a biological prosthetic aortic valve who suffered from epigastrium and right hypochondrium pain associated with intermittent night sweats. Liver biopsy showed infectious hepatitis pattern without pathognomonic features. Coxiella burnetii serology was suggestive of chronic Q fever, and modified Duke's criteria for endocarditis were also fulfilled. The authors present a brief literature review concerning chronic Q fever, emphasizing absent previous reports of chronic Q fever with hepatitis and endocarditis and no increase in inflammatory markers.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Skin biopsy. Perivascular dermatitis with purpura (arrows).
Figure 2
Figure 2
Transesophageal echocardiography. Echodense images on the aortic cups indicated by arrows. Left atrium (LA), left ventricle (LV), aorta (Ao).
Figure 3
Figure 3
Liver biopsy. polymorphic inflammatory infiltrate of the portal spaces with extravasation into the hepatic parenchyma (black arrows), cell aggregates outlining granulomas (red star), focal necrosis of hepatocytes (black star).
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

  • Coxiella burnetii - Pathogenic Agent of Q (Query) Fever.
    Gürtler L, Bauerfeind U, Blümel J, Burger R, Drosten C, Gröner A, Heiden M, Hildebrandt M, Jansen B, Offergeld R, Pauli G, Seitz R, Schlenkrich U, Schottstedt V, Strobel J, Willkommen H. Gürtler L, et al. Transfus Med Hemother. 2014 Feb;41(1):60-72. doi: 10.1159/000357107. Epub 2013 Dec 23. Transfus Med Hemother. 2014. PMID: 24659949 Free PMC article. No abstract available.
  • From Q Fever to Coxiella burnetii Infection: a Paradigm Change.
    Eldin C, Mélenotte C, Mediannikov O, Ghigo E, Million M, Edouard S, Mege JL, Maurin M, Raoult D. Eldin C, et al. Clin Microbiol Rev. 2017 Jan;30(1):115-190. doi: 10.1128/CMR.00045-16. Clin Microbiol Rev. 2017. PMID: 27856520 Free PMC article. Review.

References

    1. Brouqui P, Raoult D. Endocarditis due to rare and fastidious bacteria. Clinical Microbiology Reviews. 2001;14(1):177–207. - PMC - PubMed
    1. Fournier PE, Marrie TJ, Raoult D. Diagnosis of Q fever. Journal of Clinical Microbiology. 1998;36(7):1823–1834. - PMC - PubMed
    1. Willems H, Thiele D, Frölich-Ritter R, Krauss H. Detection of Coxiella burnetii in cow’s milk using the polymerase chain reaction (PCR) Journal of Veterinary Medicine B. 1994;41(9):580–587. - PubMed
    1. Fournier PE, Casalta JP, Habib G, Messana T, Raoult D. Modification of the diagnostic criteria proposed by the Duke Endocarditis Service to permit improved diagnosis of Q fever endocarditis. American Journal of Medicine. 1996;100(6):629–633. - PubMed
    1. Parker NR, Barraler JH, Bell AM. Q fever. The Lancet. 2006;367(9511):679–688. - PubMed

LinkOut - more resources