The changing landscape of clinical research: top grading your research center for success

Abstract

The impact of innovation and the effectiveness of research on healthcare is nothing short of remarkable; one need only to reflect on the breakthroughs of the past quarter century to understand the accomplishments of physician investigators and the benefits their research have bestowed upon society. Yet the success of any clinical trial relies heavily on the ability of the investigator to understand his/her role in compliant trial conduct, to evaluate the merits of an investigational product, the protocol design, willingness of subjects to participate in clinical trials, and the ability of his/her site to meet sponsor expectations. This article provides basic insight into the challenges and opportunities offered by clinical trial participation, while assisting new and experienced investigators in selecting an appropriate research model for their practice.