Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2012 Aug;23(8):1275-7.
doi: 10.1681/ASN.2012060615. Epub 2012 Jul 12.

Dying cells and extracellular histones in AKI: beyond a NET effect?

Diane L Rosin, Mark D Okusa
Editorial

Dying cells and extracellular histones in AKI: beyond a NET effect?

Diane L Rosin et al. J Am Soc Nephrol. 2012 Aug.
No abstract available

PubMed Disclaimer

Comment on

  • Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.
    Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ. Allam R, et al. J Am Soc Nephrol. 2012 Aug;23(8):1375-88. doi: 10.1681/ASN.2011111077. Epub 2012 Jun 7. J Am Soc Nephrol. 2012. PMID: 22677551 Free PMC article.

References

    1. Rosin DL, Okusa MD: Dangers within: DAMP responses to damage and cell death in kidney disease. J Am Soc Nephrol 22: 416–425, 2011 - PMC - PubMed
    1. Anders HJ: Toll-like receptors and danger signaling in kidney injury. J Am Soc Nephrol 21: 1270–1274, 2010 - PubMed
    1. Anders HJ, Muruve DA: The inflammasomes in kidney disease. J Am Soc Nephrol 22: 1007–1018, 2011 - PubMed
    1. Allam R, Scherbaum CR, Darisipudi MN, Mulay SR, Hägele H, Lichtnekert J, Hagemann JH, Rupanagudi KV, Ryu M, Schwarzenberger C, Hohenstein B, Hugo C, Uhl B, Reichel CA, Krombach F, Monestier M, Liapis H, Moreth K, Schaefer L, Anders HJ: Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4. J Am Soc Nephrol 23: 1375–1388, 2012 - PMC - PubMed
    1. Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A: Neutrophil extracellular traps kill bacteria. Science 303: 1532–1535, 2004 - PubMed

MeSH terms

LinkOut - more resources