Glomerular homeostasis requires a match between podocyte mass and metabolic load

Editorial

Jeffrey B Kopp. J Am Soc Nephrol. 2012 Aug.

. 2012 Aug;23(8):1273-5.

doi: 10.1681/ASN.2012060618. Epub 2012 Jul 12.

No abstract available

Comment on

Growth-dependent podocyte failure causes glomerulosclerosis.
Fukuda A, Chowdhury MA, Venkatareddy MP, Wang SQ, Nishizono R, Suzuki T, Wickman LT, Wiggins JE, Muchayi T, Fingar D, Shedden KA, Inoki K, Wiggins RC. Fukuda A, et al. J Am Soc Nephrol. 2012 Aug;23(8):1351-63. doi: 10.1681/ASN.2012030271. Epub 2012 Jul 5. J Am Soc Nephrol. 2012. PMID: 22773827 Free PMC article.

Podocyte injury: the role of proteinuria, urinary plasminogen, and oxidative stress.
Raij L, Tian R, Wong JS, He JC, Campbell KN. Raij L, et al. Am J Physiol Renal Physiol. 2016 Dec 1;311(6):F1308-F1317. doi: 10.1152/ajprenal.00162.2016. Epub 2016 Jun 22. Am J Physiol Renal Physiol. 2016. PMID: 27335373 Free PMC article.
Plasminogenuria is associated with podocyte injury, edema, and kidney dysfunction in incident glomerular disease.
Egerman MA, Wong JS, Runxia T, Mosoyan G, Chauhan K, Reyes-Bahamonde J, Anandakrishnan N, Wong NJ, Bagiella E, Salem F, Meliambro K, Li H, Azeloglu EU, Coca SG, Campbell KN, Raij L. Egerman MA, et al. FASEB J. 2020 Dec;34(12):16191-16204. doi: 10.1096/fj.202000413R. Epub 2020 Oct 18. FASEB J. 2020. PMID: 33070369 Free PMC article.
Glomerular cell cross-talk influences composition and assembly of extracellular matrix.
Byron A, Randles MJ, Humphries JD, Mironov A, Hamidi H, Harris S, Mathieson PW, Saleem MA, Satchell SC, Zent R, Humphries MJ, Lennon R. Byron A, et al. J Am Soc Nephrol. 2014 May;25(5):953-66. doi: 10.1681/ASN.2013070795. Epub 2014 Jan 16. J Am Soc Nephrol. 2014. PMID: 24436469 Free PMC article.

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