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. 1990 Dec;71(4):467-72.

CD45RA is detected in all thymocyte subsets defined by CD4 and CD8 by using three-colour flow cytometry

E B Lightstone  1 , J Marvel
Affiliations

CD45RA is detected in all thymocyte subsets defined by CD4 and CD8 by using three-colour flow cytometry

E B Lightstone et al. Immunology. 1990 Dec.

Abstract

In the mouse, using three-colour flow cytometry, the presence of CD45RA+ cells is demonstrated amongst all of the thymocyte subsets defined by expression of CD4 and CD8, i.e. amongst the double negatives, immature CD8 single positives, double-positive blasts and CD4 and CD8 single positives. This evidence is compatible with the existence of a continuous lineage of T cells expressing CD45RA which would develop from double-negative to mature single-positive T cells.

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