doi: 10.1084/jem.150.5.1277.
A T helper cell for anti-viral cytotoxic T-cell responses
- PMID: 227982
- PMCID: PMC2185695
- DOI: 10.1084/jem.150.5.1277
Item in Clipboard
A T helper cell for anti-viral cytotoxic T-cell responses
J Exp Med.
.
Abstract
We demonstrate here: (a) the existence of T helper (Th) cells that augment the generation of virus-specific cytotoxic T cells in vitro, (b) that the helper cells carry the theta and Ly 1 membrane antigens, (c) that activation of the Th effect is specific for viral antigens, and (d) that the delivery of help is not H-2 restricted.
Similar articles
-
T-T cell interactions during in vitro cytotoxic T lymphocyte responses. III. Antigen-specific T helper cells release nonspecific mediator(s) able to help induction of H-2-restricted cytotoxic T lymphocyte responses across cell-impermeable membranes.Eur J Immunol. 1980 Aug;10(8):577-82. doi: 10.1002/eji.1830100802. Eur J Immunol. 1980. PMID: 6156847
-
Primary in vitro sensitization of virus specific cytotoxic T lymphocytes.Immunology. 1978 Apr;34(4):763-9. Immunology. 1978. PMID: 82534 Free PMC article.
-
The in vivo cytotoxic T cell response to alloantigen requires a Lyt-1+ helper T lymphocyte.Transplantation. 1981 Nov;32(5):409-14. doi: 10.1097/00007890-198111000-00014. Transplantation. 1981. PMID: 6977213
-
Cell membrane antigens recognized by anti-viral and anti-trinitrophenyl cytotoxic T lymphocytes.Immunol Rev. 1981;58:73-94. doi: 10.1111/j.1600-065x.1981.tb00350.x. Immunol Rev. 1981. PMID: 6273294 Review. No abstract available.
-
An analysis of effector T cell generation and function in mice exposed to influenza A or Sendai viruses.Immunol Rev. 1981;58:5-24. doi: 10.1111/j.1600-065x.1981.tb00347.x. Immunol Rev. 1981. PMID: 6273293 Review. No abstract available.
Cited by
-
Rescue of anti-influenza A virus cytotoxic T-lymphocyte responses in chemotherapy-suppressed mice.J Virol. 1984 Jul;51(1):20-5. doi: 10.1128/JVI.51.1.20-25.1984. J Virol. 1984. PMID: 6610060 Free PMC article.
-
Hyperthermia and the generation and activity of murine influenza-immune cytotoxic T cells in vitro.J Virol. 1984 Dec;52(3):928-31. doi: 10.1128/JVI.52.3.928-931.1984. J Virol. 1984. PMID: 6333517 Free PMC article.
-
The effect of cyclophosphamide on cytotoxic T-lymphocyte responses: inhibition of helper T-cell induction in vitro.Immunology. 1983 Mar;48(3):433-8. Immunology. 1983. PMID: 6219062 Free PMC article.
-
Effect of helper T cells on the primary in vitro production of delayed-type hypersensitivity to influenza virus.J Exp Med. 1981 May 1;153(5):1029-43. doi: 10.1084/jem.153.5.1029. J Exp Med. 1981. PMID: 6166710 Free PMC article.
-
Helper activity is required for the in vivo generation of cytotoxic T lymphocytes.J Exp Med. 1982 Mar 1;155(3):768-82. doi: 10.1084/jem.155.3.768. J Exp Med. 1982. PMID: 6801178 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
