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Review
. 2012 Jul;30(3):535-45.
doi: 10.1016/j.det.2012.04.012.

New diagnostic aids for melanoma

Laura Korb Ferris  1 , Ryan J Harris
Affiliations
Review

New diagnostic aids for melanoma

Laura Korb Ferris et al. Dermatol Clin. 2012 Jul.

Abstract

Detection of melanoma at an early stage is crucial to improving survival rates in melanoma. Accurate diagnosis by current techniques including dermatoscopy remains difficult, and new tools are needed to improve our diagnostic abilities. This article discusses recent advances in diagnostic techniques including confocal scanning laser microscopy, MelaFind, SIAscopy, and noninvasive genomic detection, as well as other future possibilities to aid in diagnosing melanoma. Advantages and barriers to implementation of the various technologies are also discussed.

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Conflict of interest statement

Conflicts of Interest:

Dr. Ferris: Served as an investigator and consultant for MELA Sciences and as an investigator for DermTech International

Dr. Harris: No conflicts of interest to declare

Figures

Figure 1
Figure 1
Dermatoscopic image of an invasive melanoma.
Figure 2
Figure 2
Histopathology (A) and confocal microscopy (B) from an in situ melanoma. Images courtesy of Harold Rabinovitz, MD.
Figure 2
Figure 2
Histopathology (A) and confocal microscopy (B) from an in situ melanoma. Images courtesy of Harold Rabinovitz, MD.
Figure 3
Figure 3
Figure 3A: A representative schematic of multispectral image analysis of a pigmented lesion showing 10 images from multiple depths within the skin. Figure 3B: Actual images from multispectral image analysis showing a digitally detected margin from most superficial (430nm) to deepest (950nm)
Figure 3
Figure 3
Figure 3A: A representative schematic of multispectral image analysis of a pigmented lesion showing 10 images from multiple depths within the skin. Figure 3B: Actual images from multispectral image analysis showing a digitally detected margin from most superficial (430nm) to deepest (950nm)
See this image and copyright information in PMC

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