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. 2012 Dec;22(12):1624-6.
doi: 10.1038/cr.2012.109. Epub 2012 Jul 17.

Meiotic DSBs and the control of mammalian recombination

Kenneth Paigen  1 , Petko Petkov
Affiliations

Meiotic DSBs and the control of mammalian recombination

Kenneth Paigen et al. Cell Res. 2012 Dec.

Abstract

The laboratories of Galina Petukhova and R Daniel Camerini-Otero have achieved significant technical advances in determining the genome-wide sites of DNA double-strand breaks (DSBs) where the process of genetic exchange between chromatids during meiosis begins. Applying the new approaches to male meiosis in mice, their experimental results considerably increase our insights into the nature and regulation of these processes.

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