Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2010 Dec 14:2010:bcr0720092112.
doi: 10.1136/bcr.07.2009.2112.

Transient osteoporosis associated with pregnancy: use of bisphosphonate in treating a lactating mother

N G Shenker  1 , M F Shaikh, A S M Jawad
Affiliations
Case Reports

Transient osteoporosis associated with pregnancy: use of bisphosphonate in treating a lactating mother

N G Shenker et al. BMJ Case Rep. .

Abstract

Transient osteoporosis is a rare condition causing regional pain, immobility and functional compromise. The authors present the case of a pregnant lady with multiple sites of transient osteoporosis, including a stress fracture, successfully treated with intravenous pamidronate and a physical rehabilitation programme. The authors discuss the mechanisms for the syndrome and its overlap with complex regional pain syndrome type I; as well as the implications of bisphosphonate administration to a nursing mother. The authors also highlight the advantages of MRI over standard radiography when investigating unexplained foot pain.

PubMed Disclaimer

Conflict of interest statement

Competing interests None.

Figures

Figure 1
Figure 1
(A) Normal lumbar spine. (B) Widespread bony oedema and joint effusion affecting left hip with localised bony oedema affecting right hip.
Figure 1
Figure 1
(A) Normal lumbar spine. (B) Widespread bony oedema and joint effusion affecting left hip with localised bony oedema affecting right hip.
Figure 2
Figure 2
(A) MRI demonstrating stress fracture of talar dome. (B) Normal ankle x-ray taken at a similar time. (C) Bony oedema affecting tibial plateau.
Figure 2
Figure 2
(A) MRI demonstrating stress fracture of talar dome. (B) Normal ankle x-ray taken at a similar time. (C) Bony oedema affecting tibial plateau.
Figure 2
Figure 2
(A) MRI demonstrating stress fracture of talar dome. (B) Normal ankle x-ray taken at a similar time. (C) Bony oedema affecting tibial plateau.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Curtiss PH, Jr, Kincaid WE. Transitory demineralization of the hip in pregnancy. A report of three cases. J Bone Joint Surg Am 1959;41-A:1327–33 - PubMed
    1. Arayssi TK, Tawbi HA, Usta IM, et al. Calcitonin in the treatment of transient osteoporosis of the hip. Semin Arthritis Rheum 2003;32:388–97 - PubMed
    1. Berger CE, Kröner AH, Minai-Pour MB, et al. Biochemical markers of bone metabolism in bone marrow edema syndrome of the hip. Bone 2003;33:346–51 - PubMed
    1. Siminoski K, Fitzgerald AA, Flesch G, et al. Intravenous pamidronate for treatment of reflex sympathetic dystrophy during breast feeding. J Bone Miner Res 2000;15:2052–5 - PubMed
    1. Carmona-Ortells L, Carvajal-Méndez I, García-Vadillo JA, et al. Transient osteoporosis of the hip: successful response to deflazacort. Clin Exp Rheumatol 1995;13:653–5 - PubMed

Publication types