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Case Reports
. 2012 Jul 13:2012:bcr2012006452.
doi: 10.1136/bcr-2012-006452.

Paying more than lip service to an oral lesion: a case of plasmablastic lymphoma

Yasbanoo Moayedi  1 , Erik Steven Venos, Hasan Ghaffar, Kevin A Gough, Lisa K Hicks
Affiliations
Case Reports

Paying more than lip service to an oral lesion: a case of plasmablastic lymphoma

Yasbanoo Moayedi et al. BMJ Case Rep. .

Abstract

Plasmablastic lymphoma (PBL) is a variant of lymphoma originally described in the oral cavity of patients with advanced HIV. Our patient developed PBL despite well-controlled HIV and a CD4 count greater than 800 cells/µl. A drug interaction with an inhaled corticosteroid and ritonavir likely contributed to the development of this malignancy through increased immune suppression.

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Conflict of interest statement

Competing interests: None.

Figures

Figure 1
Figure 1
(A) A flesh-coloured lesion measuring 4 cm in diameter on the mucosal surface of the left upper lip. (B) Violaceous striae on the abdomen.
Figure 2
Figure 2
(A) H&E stain demonstrates medium to large cells with eccentrically placed nuclei and brisk mitotic activity (×600). (B) In situ hybridisation of Epstein-Barr virus positive in the malignant cells (×600).
See this image and copyright information in PMC

References

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