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Review
. 2012 Sep;160(1):72-82.
doi: 10.1104/pp.112.201905. Epub 2012 Jul 16.

Ubiquitin and plant viruses, let's play together!

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Review

Ubiquitin and plant viruses, let's play together!

Catherine Alcaide-Loridan et al. Plant Physiol. 2012 Sep.
No abstract available

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Figures

Figure 1.
Figure 1.
The UPS. Ubiquitination of a target protein substrate occurs through the sequential action of three classes of enzymes: a Ub-activating enzyme (E1), a Ub-conjugating enzyme (E2), and a Ub ligase (E3). It can be reversed by the action of DUBs. By reiterative rounds of ubiquitination, polymeric Ub chains can be generated, whose function depends on the type of Ub chains attached to the target substrate.
Figure 2.
Figure 2.
Schematic representation of an SCF-type E3 ligase. The generic architecture of an SCF complex is shown. The F-box protein serves as a substrate recognition subunit. The activity of the SCF complexes is regulated by conjugation of the Cullin subunit to the UbL RUB1. The COP9 signalosome contributes to this regulation due to its derubylating activity.

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