Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Aug;46(2):257-63.
doi: 10.1002/mus.23307.

Utilizing a handheld electrode array for localized muscle impedance measurements

Pushpa Narayanaswami  1 , Andrew J Spieker, Phillip Mongiovi, John C Keel, Stefan C Muzin, Seward B Rutkove
Affiliations

Utilizing a handheld electrode array for localized muscle impedance measurements

Pushpa Narayanaswami et al. Muscle Nerve. 2012 Aug.

Abstract

Introduction: Electrical impedance myography (EIM) is a noninvasive technique used for assessment of muscle health in which a high-frequency, low-amplitude electric current is applied to the skin overlying a muscle, and the resulting surface voltage is measured. We have previously used adhesive electrodes, application of which is inconvenient. We present data using a handheld electrode array (HEA) that we devised to expedite the EIM procedure in a clinical setting.

Methods: Thirty-four healthy volunteers and 24 radiculopathy subjects underwent EIM testing using the HEA and adhesive electrodes.

Results: The HEA was shown to have good test-retest reproducibility, with intraclass correlation coefficients as high as 0.99. HEA data correlated strongly with data from adhesive electrodes, ρ = 0.85 in healthy volunteers (P < 0.001) and ρ = 0.75 in radiculopathy subjects (P < 0.001).

Conclusions: These data support the potential use of a handheld array for performing rapid localized surface impedance measurements.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Handheld electrode array.
Figure 2
Figure 2
Test-retest reproducibility of 50 kHz phase with HEA in all healthy subjects (gray trend line) and radiculopathy patients (black trend line).
Figure 3
Figure 3
Comparison between HEA and adhesive electrodes 50 kHz phase in healthy subjects (gray trend line) and radiculopathy patients (black trend line).
Figure 4
Figure 4
Method comparison between HEA and adhesive electrodes in deltoid and medial gastrocnemius 50 kHz phase.
See this image and copyright information in PMC

References

    1. Rutkove SB, Aaron R, Shiffman CA. Localized bioimpedance analysis in the evaluation of neuromuscular disease. Muscle Nerve. 2002;25:390–397. - PubMed
    1. Shiffman CA, Aaron R, Amoss V, Therrien J, Coomler K. Resistivity and phase in localized BIA. Phys Med Biol. 1999;44:2409–2429. - PubMed
    1. Rutkove SB, Esper GJ, Lee KS, Aaron R, Shiffman CA. Electrical impedance myography in the detection of radiculopathy. Muscle Nerve. 2005;32:335–341. - PubMed
    1. Rutkove SB, Zhang H, Schoenfeld DA, Raynor EM, Shefner JM, Cudkowicz ME, Chin AB, Aaron R, Shiffman CA. Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials. Clin Neurophysiol. 2007;118:2413–2418. - PMC - PubMed
    1. Tarulli A, Esper GJ, Lee KS, Aaron R, Shiffman CA, Rutkove SB. Electrical impedance myography in the bedside assessment of inflammatory myopathy. Neurology. 2005;65:451–452. - PubMed

Publication types