[An analysis of the expression of the mutant angora-Y gene in the mouse]

Abstract

We studied the rate and duration of the growth of G1 and G3 hairs in mice homozygous for angora-Y mutant gene (goY). The follicular diameter of G3 hairs and the growth rate of G1 and G3 hairs in goY/goY mice do not differ from normal. However, the duration of growth period of all four studied types of hairs in goY/goY mice is longer than in the normal phenotype. Growth of the guard hairs G1 and G3 in mutants continues longer than in the normal phenotype by 7 and 3 days, respectively. For other hair types G1 and G3 (awl, auchene, zigzag) the duration of the growth period is approximately 3 days longer than in the control. As a result in goY/goY mice guard hairs G1 and G3 which have completed growth are 2 and 1.5 times longer than in +/+ mice. Other types of G1 hairs in mutants are longer by 50% and G3 hairs by 30% than in the wild type.