Susceptibility of human cell lines to feline leukemia virus and feline sarcoma virus
- PMID: 228103
Susceptibility of human cell lines to feline leukemia virus and feline sarcoma virus
Abstract
The susceptibility of human fibroblasts and human lymphoid cell lines to feline leukemia virus (FeLV) and feline sarcoma virus (FeSV) was investigated. Human cells were highly sensitive to infection by FeLV subgroups B and C and FeSV but resistant to infection by FeLV subgroup A. The cells became infected, produced infectious virus, and displayed no differences in morphology or viability. T-cell lines appeared to be more sensitive to FeLV and FeSV infection and to produce more virus than did autochthonous B-cells. B-cell lines with membrane IgG appeared more resistant to infection than did those with no membrane IgG.
Similar articles
-
Protection of cats against progressive fibrosarcomas and persistent leukemia virus infection by vaccination with feline leukemia cells.J Natl Cancer Inst. 1980 Dec;65(6):1285-92. J Natl Cancer Inst. 1980. PMID: 6253714
-
Determinants of susceptibility and resistance to feline leukemia virus infection. II. Susceptibility of feline lymphocytes to productive feline leukemia virus infection.J Natl Cancer Inst. 1981 Oct;67(4):899-910. J Natl Cancer Inst. 1981. PMID: 6268886
-
Establishment of two canine sarcoma cell lines: productive infection with feline leukemia virus.J Natl Cancer Inst. 1975 Aug;55(2):345-52. J Natl Cancer Inst. 1975. PMID: 169374
-
The host range and interference properties of two closely related feline leukemia variants suggest that they use distinct receptors.Virology. 1998 Mar 15;242(2):366-77. doi: 10.1006/viro.1997.9008. Virology. 1998. PMID: 9514965
-
Quantification of endogenous and exogenous feline leukemia virus sequences by real-time PCR assays.Vet Immunol Immunopathol. 2008 May 15;123(1-2):129-33. doi: 10.1016/j.vetimm.2008.01.027. Epub 2008 Jan 19. Vet Immunol Immunopathol. 2008. PMID: 18295344 Review.
Cited by
-
Could FIV zoonosis responsible of the breakdown of the pathocenosis which has reduced the European CCR5-Delta32 allele frequencies?Virol J. 2008 Oct 16;5:119. doi: 10.1186/1743-422X-5-119. Virol J. 2008. PMID: 18925940 Free PMC article.
-
Feline sarcoma virus induced in vitro progression from premalignant to neoplastic transformation of human diploid cells.In Vitro. 1980 Sep;16(9):813-22. doi: 10.1007/BF02619317. In Vitro. 1980. PMID: 6250976
-
Sequence organization of feline leukemia virus DNA in infected cells.Nucleic Acids Res. 1980 Aug 11;8(15):3287-305. doi: 10.1093/nar/8.15.3287. Nucleic Acids Res. 1980. PMID: 6255412 Free PMC article.
-
Uterine adenocarcinoma with feline leukemia virus infection.Lab Anim Res. 2011 Dec;27(4):347-51. doi: 10.5625/lar.2011.27.4.347. Epub 2011 Dec 19. Lab Anim Res. 2011. PMID: 22232645 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources