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. 2012 May;27(3):192-5.
doi: 10.5001/omj.2012.44.

Fibromyalgia syndrome: an overview of pathophysiology, diagnosis and management

Firdous Jahan, Kashmira Nanji, Waris Qidwai, Rizwan Qasim

Fibromyalgia syndrome: an overview of pathophysiology, diagnosis and management

Firdous Jahan et al. Oman Med J. 2012 May.

Abstract

Fibromyalgia Syndrome (FMS) is a chronic condition causing pain, stiffness, and tenderness of the muscles, tendons, and joints. It is also characterized by restless sleep, tiredness, fatigue, anxiety, depression, and disturbances in bowel functions. The etiology of fibromyalgia remains unknown, but recent advances and discoveries have helped to unravel some of the mysteries of this disease. Research highlights some of the biochemical, metabolic, and immunoregulatory abnormalities associated with fibromyalgia. Management of FMS at the present time is very difficult as it has multiple etiological factors and psychological predispositions; however, a patient centered approach is essential to handle this problem.

Keywords: Clinical features; Fibromyalgia; Pathophysiology and management of fibromyalgia; Quality of life.

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