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. 2012 May;27(3):212-6.
doi: 10.5001/omj.2012.48.

Prevalence and risk factors of diabetic nephropathy in omani type 2 diabetics in Al-dakhiliyah region

Abdulhakeem Hamood Alrawahi, Syed Gauhar A Rizvi, Dawood Al-Riyami, Zaher Al-Anqoodi

Prevalence and risk factors of diabetic nephropathy in omani type 2 diabetics in Al-dakhiliyah region

Abdulhakeem Hamood Alrawahi et al. Oman Med J. 2012 May.

Abstract

Objective: To assess the prevalence and risk factors of diabetic nephropathy among Omani type 2 diabetics in Al-Dakhiliyah region of the Sultanate of Oman.

Methods: A cross-sectional and a case control study designs were used to assess the prevalence and risk factors respectively. For the prevalence study a sample of 699 diabetic subjects were selected randomly from two polyclinics in Al-Dakhiliyah region; Sumail and Nizwa polyclinics. For the case control study, a sample consisting of 215 cases and 358 controls were randomly selected from those who were included in the cross-sectional study. A well designed questionnaire has been used to collect data regarding the disease and risk factors. Data was analyzed using SPSS19 statistical program.

Results: Total prevalence of diabetic nephropathy was calculated as 42.5% (95% C.I: 38.83% - 46.15%). The difference in the prevalence in the two polyclinic catchment area was not significant. The prevalence was significantly higher among males (51.6%) compared to females (36.5%). Crude analysis of the risk factors showed significant association between diabetic nephropathy and the following factors; male gender, decreased literacy, long duration of diabetes mellitus, hypertension, retinopathy, neuropathy, family history of diabetic nephropathy, poor glycemic control (high HbA1c), and hypertriglyceridemia. Multivariate analysis showed the following factors to be independent risk factors; male gender, decreased literacy, long duration of diabetes, family history of diabetic nephropathy and poor glycaemic control (high HbA1c).

Conclusion: The prevalence of diabetic nephropathy in this study was 42.5% and the significant risk factors associated with it included male gender, decreased literacy, long duration of diabetes, family history of diabetic nephropathy and poor glycemic control (high HbA1c).

Keywords: Albuminuria; Diabetic nephropathy; Omani; Prevalence; Risk factors; Type 2 diabetes.

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References

    1. Evans TC, Capell P. Diabetic nephropathy. Clin Diabetes 2000;18(1). http://journal.diabetes.org/clinicaldiabetes/v18n12000/ Pg7.htm Accessed 22 May 2011.
    1. Ritz E, Orth SR. Nephropathy in patients with type 2 diabetes mellitus. N Engl J Med 1999. Oct;341(15):1127-1133 10.1056/NEJM199910073411506 - DOI - PubMed
    1. U.S. Renal Data System. USRDS 2005 Annual Data Report: Atlas of End-Stage Renal Disease in the United States, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, 2005.
    1. American Diabetic Association. Nephropathy in diabetes.Diabetic care. Available at: http://care.diabetesjournals.org/content/26/6/1781.full Accessed on May 21, 2011.
    1. Stengel B, Billon S, Van Dijk PC, Jager KJ, Dekker FW, Simpson K, et al. Trends in the incidence of renal replacement therapy for end-stage renal disease in Europe, 1990-1999. Nephrol Dial Transplant 2003. Sep;18(9):1824-1833 10.1093/ndt/gfg233 - DOI - PubMed

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