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. 2012 Jul 20;13(7):164.
doi: 10.1186/gb-2012-13-7-164.

piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense

Allison C Billi, Mallory A Freeberg, John K Kim

piRNAs and siRNAs collaborate in Caenorhabditis elegans genome defense

Allison C Billi et al. Genome Biol. .

Abstract

Caenorhabditis elegans piRNAs promote genome surveillance by triggering siRNA-mediated silencing of nonself DNA in competition with licensing programs that support endogenous gene expression.

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