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Review
. 2012 Nov 29;120(23):4488-95.
doi: 10.1182/blood-2012-05-423236. Epub 2012 Jul 20.

Point/counterpoint: early-stage Hodgkin lymphoma and the role of radiation therapy

Ralph M Meyer  1 , Richard T Hoppe
Affiliations
Review

Point/counterpoint: early-stage Hodgkin lymphoma and the role of radiation therapy

Ralph M Meyer et al. Blood. .

Abstract

The results of recent clinical trials for the management of limited-stage Hodgkin lymphoma have led to considerable debate, especially regarding the role of radiation therapy. This review highlights those recent trials and provides perspectives regarding their interpretation from a radiation oncologist and a hematologist. The trial protocol is available at http://www.nejm.org/doi/suppl/10.1056/NEJMoa1111961/suppl_file/nejmoa1111961_protocol.pdf.

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References

    1. Engert A, Plutschow A, Eich HT, et al. Reduced treatment intensity in patients with early-stage Hodgkin's lymphoma. N Engl J Med. 2010;363(7):640–652. - PubMed
    1. Meyer RM, Gospodarowicz MK, Connors JM, et al. ABVD alone versus radiation-based therapy in limited-stage Hodgkin's lymphoma. N Engl J Med. 2012;366(5):399–408. - PMC - PubMed
    1. Hoppe RT, Advani RH, Ai WZ, et al. Hodgkin lymphoma. J Natl Compr Canc Netw. 2011;9(9):1020–1058. - PubMed
    1. Pusey WA. Cases of sarcoma and of Hodgkin's disease treated by exposure to X-rays: a preliminary report. JAMA. 1902;38:166–169.
    1. Gilbert R. Notre Methode De Roentgentherapie De La Lymphogranulomatose (Hodgkin): Resultats Eloignes. Acta Radiol. 1931:12.

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