Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1990 Oct;2(10):311-20.

Molecular genetics of eukaryotic DNA excision repair

J H Hoeijmakers  1 , D Bootsma
Affiliations
  • PMID: 2282248
Review

Molecular genetics of eukaryotic DNA excision repair

J H Hoeijmakers et al. Cancer Cells. 1990 Oct.

Abstract

DNA repair plays a key role in the prevention of carcinogenesis and mutagenesis. Defective DNA repair has been implicated in various human hereditary disorders that predispose affected individuals to cancer. This article reviews our current understanding of one of major DNA repair systems--the nucleotide excision repair pathway--with special emphasis on the novel findings that have emerged from molecular genetic analysis of yeast and cultured mammalian cells.

PubMed Disclaimer

Publication types