A feasibility analysis of implementing interventions for discordant couples in 14 African countries: implications for epidemic control
- PMID: 22824631
- PMCID: PMC4726451
- DOI: 10.1097/QAD.0b013e328357f783
A feasibility analysis of implementing interventions for discordant couples in 14 African countries: implications for epidemic control
Abstract
We find interventions targeting serodiscordant couples (SDC) may not be feasible in countries where HIV prevalence is less than 5%, because only 3-19/1000 individuals are HIV-positive/negative and in SDC. Interventions may be feasible in countries where prevalence is greater than 10%, because 34-48/1000 individuals are HIV-positive/negative and in SDC. We calculated that 20-27% of all HIV-positive individuals, but less than 6% of all HIV-negative individuals, are in SDC. Consequently, targeting HIV-positive partners could significantly reduce transmission, whereas targeting HIV-negative partners may have little impact.
Conflict of interest statement
References
-
- World Health Organization. Guidance on couples HIV testing and couselling including antiretroviral therapy for treatment and prevention in serodiscordant couples: recommendations for a public health approach. 2012 Apr; - PubMed
-
- Eyawo O, de Walque D, Ford N, Gakii G, Lester RT, Mills EJ. HIV status in discordant couples in sub-Saharan Africa: a systematic review and meta-analysis. Lancet Infect Dis. 2010;10:770–777. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Medical