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Review
. 2012 Sep;61(3):365-72.
doi: 10.2332/allergolint.12-RAI-0461. Epub 2012 Jul 25.

Exhaled nitric oxide (FeNO) as a non-invasive marker of airway inflammation

Mitsuru Munakata  1
Affiliations
Free article
Review

Exhaled nitric oxide (FeNO) as a non-invasive marker of airway inflammation

Mitsuru Munakata. Allergol Int. 2012 Sep.
Free article

Abstract

Nitric oxide (NO), previously very famous for being an environmental pollutant in the field of pulmonary medicine, is now known as the smallest, lightest, and most famed molecule to act as a biological messenger. Furthermore, recent basic researches have revealed the production mechanisms and physiological functions of nitric oxide in the lung, and clinical researches have been clarifying its tight relation to airway inflammation in asthma. On the bases of this knowledge, fractional nitric oxide (FeNO) has now been introduced as one of the most practical tools for the diagnosis and management of bronchial asthma.

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