Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2012 Oct;12(5):456-64.
doi: 10.1007/s11882-012-0287-y.

Assessment of environmental cockroach allergen exposure

Affiliations
Review

Assessment of environmental cockroach allergen exposure

Ginger L Chew. Curr Allergy Asthma Rep. 2012 Oct.

Abstract

In the past, cockroach allergen exposure assessment mainly focused on settled dust in homes in low-income urban cities in the United States. That choice was not wrong; without measureable levels of cockroach allergen, it is difficult to show associations with any home characteristics, much less with health outcomes (e.g., allergy, asthma). However, recent studies in other suburban areas, schools, and other countries have elucidated the importance of cockroach allergen in these environments too. In addition, characterizing the underlying factors that give rise to cockroach allergen exposure (or protect against it) can lead to more targeted public health interventions. This review discusses different approaches to sampling indoor environments, interprets recent asthma and allergy studies, compares cockroach allergen levels from past studies with those of recent studies, and describes strategies for decreasing exposures.

PubMed Disclaimer

Figures

Figure 1
Figure 1
A timeline of cockroach allergen measurements (Bla g 1) in childhood asthma studies

References

    1. Arruda LK. Cockroach allergens. Curr Allergy Asthma Rep. 2005;5(5):411–6. - PubMed
    1. Sudha VT, Arora N, Singh BP. Serine protease activity of Per a 10 augments allergen-induced airway inflammation in a mouse model. Eur J Clin Invest. 2009;39(6):507–16. - PubMed
    1. Reese TA, et al. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature. 2007;447(7140):92–6. - PMC - PubMed
    1. Elias JA, et al. Chitinases and chitinase-like proteins in T(H)2 inflammation and asthma. J Allergy Clin Immunol. 2005;116(3):497–500. - PubMed
    1. de Blay F, et al. Dust and airborne exposure to allergens derived from cockroach (Blatella germanica) in low-cost public housing in Strausbourg (France) J Allergy Clin Immunol. 1997;99:107–112. - PubMed