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Comment
. 2012 Jul 24;79(4):e33-6.
doi: 10.1212/WNL.0b013e3182604385.

Journal Club: a randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

Peter Pressman  1 , Jay A Gottfried
Affiliations
Comment

Journal Club: a randomized, double-blind, placebo-controlled trial of simvastatin to treat Alzheimer disease

Peter Pressman et al. Neurology. .
No abstract available

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References

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    1. Fassbender K, Simons M, Bergmann C, et al. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc Natl Acad Sci USA 2001;98:5856–5861 . - PMC - PubMed
    1. Simons M, Schwarzler F, Lutjohann D, et al. Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: a 26-week randomized, placebo-controlled, double-blind trial. Ann Neurol 2002;52:346–350 . - PubMed
    1. Reitz C. Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations. J Alzheimer Dis 2011;28:1–19 . - PMC - PubMed

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