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. 2011 Jul 20;1(1):7.
doi: 10.1186/2191-1991-1-7.

Quality of life results of balloon kyphoplasty versus non surgical management for osteoporotic vertebral fractures in Germany

Daniela Eidt-Koch  1 , Wolfgang Greiner
Affiliations

Quality of life results of balloon kyphoplasty versus non surgical management for osteoporotic vertebral fractures in Germany

Daniela Eidt-Koch et al. Health Econ Rev. .

Abstract

Background: To compare improvement in quality of life (QoL) and symptoms' relief in vertebral compression fractures (VCF) due to osteoporosis for patients undergoing balloon kyphoplasty (BKP) to those undergoing non-surgical management (NSM) in a real-life setting.

Methods: In this prospective, comparative study, quality-of-life was evaluated in eight centres in Germany between 2005 and 2008, for 82 patients, with the EQ-5D questionnaire, and the Roland Morris Disability Questionnaire (RMDQ).

Results: BKP patients demonstrated a statistical and clinical significant higher improvement in EQ-5D than NSM patients, 0.44 and 0.25 from baseline to 12 months, respectively. Moreover, BKP patients showed a clinically relevant improvement in the RMDQ by 6.25 from baseline to 12 months, whereas NSM patients had no significant improvement in the RMDQ.

Conclusions: This study demonstrates for VCF patients that in real-life quality of life for BKP patients improves more than for NSM patients; confirming the results of a large randomized clinical trial.

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Figures

Figure 1
Figure 1
Distribution of EQ-5D dimensions for BKP versus NSM patients.
Figure 2
Figure 2
EQ-5D Visual Analogue Scale (VAS) according to study groups.
See this image and copyright information in PMC

References

    1. World Health Organization. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. WHO Technical Report Series, No. 843. Geneva. 1994. - PubMed
    1. Cummings SR, Melton LJ. Epidemiology and outcomes of osteoporotic fractures. Lancet. 2002;359:1761–1767. doi: 10.1016/S0140-6736(02)08657-9. - DOI - PubMed
    1. Sambrook P, Cooper C. Osteoporosis. Lancet. 2006;367(9527):2010–2018. doi: 10.1016/S0140-6736(06)68891-0. - DOI - PubMed
    1. Becker S, Ogon M. In: Ballonkyphoplastie. Becker S, Ogon M, editor. Wien: Springer Verlag; 2006. Epidemiology of osteoporosis [German] pp. 1–3.
    1. Lau E, Ong K, Kurtz S, Schmier J, Edidin A. Mortality following the diagnosis of a vertebral compression fracture in the Medicare population. J Bone Joint Surg Am. 2008;90:1479–1486. doi: 10.2106/JBJS.G.00675. - DOI - PubMed

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