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. 2012 Aug 13;18(33):10092-142.
doi: 10.1002/chem.201201539. Epub 2012 Jul 24.

Direct α-functionalization of saturated cyclic amines

Emily A Mitchell  1 , Aldo Peschiulli, Nicolas Lefevre, Lieven Meerpoel, Bert U W Maes
Affiliations

Direct α-functionalization of saturated cyclic amines

Emily A Mitchell et al. Chemistry. .

Abstract

Recent advances in synthetic methods for the direct α-functionalization of saturated cyclic amines are described. Methods are categorized according to the in situ formed reactive intermediate (α-amino cation, α-amino anion, and α-amino radical). Transition-metal-catalyzed reactions involving other intermediates have been treated as a separate and fourth class.

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