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. 2012:2012:940269.
doi: 10.1155/2012/940269. Epub 2012 Jul 8.

Conservative management of unusual keratinising squamous metaplasia of the bladder in a 28-year-old female and overview of the literature

Fernando Vázquez Alonso  1 , Raquel Berrio Campos, Ignacio Puche Sanz, Manuel Segura Sánchez, Jose Miguel Molina Hernandez, Jose Francisco Flores Martin, Jose Manuel Cózar Olmo
Affiliations

Conservative management of unusual keratinising squamous metaplasia of the bladder in a 28-year-old female and overview of the literature

Fernando Vázquez Alonso et al. Case Rep Urol. 2012.

Abstract

Keratinizing squamous metaplasia of the bladder is rare and is usually associated with urinary tract infections and chronic irritation. It is considered a precancerous condition of squamous cell carcinoma, especially when more than 50% of the bladder surface is affected. Medical treatment cannot eradicate this lesion. When it is limited to a small area of the bladder, transurethral resection is possible. Annual cystoscopy with multiple biopsies as well as annual upper tract imaging is proposed in the follow up of these patients. We present a preliminary 2-year followup report of a keratinizing squamous metaplasia of the bladder in a 28-year-old female patient with no previous risk factors.

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Figures

Figure 1
Figure 1
The cystoscopy revealed a whitish thin plaque clearly differentiated from the normal mucosa of the bladder trigone.
Figure 2
Figure 2
Squamous metaplasia of the bladder covered by a thick keratin layer.
See this image and copyright information in PMC

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References

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