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. 1977;3(4):250-5.
doi: 10.1159/000117610.

Thphenidate

R Kadouch, R H Belmaker, R P Ebstein, L Peres

Thphenidate

R Kadouch et al. Neuropsychobiology. 1977.

Abstract

Plasma cyclic-AMP responses to adrenergic agonists are due to stimulation of the peripheral beta-adrenergic receptor. Mood responses to stimulants are thought to be due to actions leading to stimulation of central catecholamine receptors. To determine if a peripheral measure of receptor sensitivity could predict central mood effects of stimulants, the plasma cyclic-AMP response and the mood response to intravenous methylphenidate were determined simultaneously in 13 subjects. No correlation between the two responses was found.

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