Methods Guide for Medical Test Reviews [Internet]
- PMID: 22834019
- Bookshelf ID: NBK98241
Methods Guide for Medical Test Reviews [Internet]
Excerpt
Effectiveness and Comparative Effectiveness Reviews, systematic reviews of existing research on the effectiveness, comparative effectiveness, and comparative harms of different medical tests, are intended to provide relevant evidence to inform real-world health care decisions for patients, providers, and policymakers. In an effort to improve the transparency, consistency, and scientific rigor of the work of the Effective Health Care (EHC) Program, the Agency for Healthcare Research and Quality (AHRQ), the Scientific Resource Center, and the Evidence-based Practice Centers (EPCs), have developed this Methods Guide for Medical Test Reviews (also referred to as the Medical Test Methods Guide). We intend it to serve as a resource for the EPCs as well as for other investigators interested in conducting systematic reviews on medical tests. We hope it will be a practical guide both for those who prepare the systematic reviews and those who use them in clinical practice, research development, and in making policy decisions.
Sections
- Preface
- AHRQ’s Evidence-Based Practice Centers
- The Effective Health Care Program
- List of Authors
- List of Peer Reviewers
- Editorial: Methods Guide for Authors of Systematic Reviews of Medical Tests: A Collaboration Between the Agency for Healthcare Research and Quality (AHRQ) and the Journal of General Internal Medicine
- 1. Introduction to the Methods Guide for Medical Test Reviews
- 2. Developing the Topic and Structuring Systematic Reviews of Medical Tests: Utility of PICOTS, Analytic Frameworks, Decision Trees, and Other Frameworks
- 3. Choosing the Important Outcomes for a Systematic Review of a Medical Test
- 4. Effective Search Strategies for Systematic Reviews of Medical Tests
- 5. Assessing Risk of Bias as a Domain of Quality in Medical Test Studies
- 6. Assessing Applicability of Medical Test Studies in Systematic Reviews
- 7. Grading a Body of Evidence on Diagnostic Tests
- 8. Meta-Analysis of Test Performance When There Is a “Gold Standard”
- 9. Options for Summarizing Medical Test Performance in the Absence of a “Gold Standard”
- 10. Deciding Whether To Complement a Systematic Review of Medical Tests With Decision Modeling
- 11. Challenges in and Principles for Conducting Systematic Reviews of Genetic Tests Used as Predictive Indicators
- 12. Systematic Review of Prognostic Tests
- Appendix: Test Performance Metrics
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