Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2012 Jun;89(6):287-93.

A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris

Zoe Diana Draelos  1 , Alan R Shalita, Diane Thiboutot, Christian Oresajo, Margarita Yatskayer, Susanna Raab
Affiliations
  • PMID: 22838094
Randomized Controlled Trial

A multicenter, double-blind study to evaluate the efficacy and safety of 2 treatments in participants with mild to moderate acne vulgaris

Zoe Diana Draelos et al. Cutis. 2012 Jun.

Abstract

Acne treatment regimens have changed due to the recent over-the-counter (OTC) switch of all prescription benzoyl peroxide (BPO) topical preparations. The elimination of prescription single-agent BPO products means that dermatologists must select from a variety of OTC formulations to utilize the time-tested efficacy of BPO in the treatment of mild to moderate acne. Our research compared the efficacy and safety of an OTC BPO 5.5% formulation with lipohydroxy acid and tretinoin cream 0.025% with prescription clindamycin 1%-BPO 5% gel and tretinoin cream 0.025%. Parity was demonstrated between the 2 treatment regimens at 12 weeks.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Topical benzoyl peroxide for acne.
    Yang Z, Zhang Y, Lazic Mosler E, Hu J, Li H, Zhang Y, Liu J, Zhang Q. Yang Z, et al. Cochrane Database Syst Rev. 2020 Mar 16;3(3):CD011154. doi: 10.1002/14651858.CD011154.pub2. Cochrane Database Syst Rev. 2020. PMID: 32175593 Free PMC article.
  • The Use of Lipohydroxy Acid in Skin Care and Acne Treatment.
    Zeichner JA. Zeichner JA. J Clin Aesthet Dermatol. 2016 Nov;9(11):40-43. Epub 2016 Nov 1. J Clin Aesthet Dermatol. 2016. PMID: 28210389 Free PMC article. Review.

Publication types

MeSH terms

LinkOut - more resources