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. 2012 Aug;18(8):1322-5.
doi: 10.3201/eid1808.111053.

Klebsiella pneumoniae in gastrointestinal tract and pyogenic liver abscess

Chang-Phone Fung  1 , Yi-Tsung Lin, Jung-Chung Lin, Te-Li Chen, Kuo-Ming Yeh, Feng-Yee Chang, Han-Chuan Chuang, Hau-Shin Wu, Chih-Peng Tseng, L Kristopher Siu
Affiliations

Klebsiella pneumoniae in gastrointestinal tract and pyogenic liver abscess

Chang-Phone Fung et al. Emerg Infect Dis. 2012 Aug.

Abstract

To determine the role of gastrointestinal carriage in Klebsiella pneumoniae liver abscess, we studied 43 patients. Bacterial isolates from liver and fecal samples from 10 patients with this condition and 7 healthy carriers showed identical serotypes and genotypes with the same virulence. This finding indicated that gastrointestinal carriage is a predisposing factor for liver abscess.

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Figures

Figure 1
Figure 1
Pulsed-field gel electrophoresis of randomly selected isolates of Klebsiella pneumoniae from 17 patients with liver abscess, Taiwan, January 2009–December 2010. DNA fragments were subjected to electrophoresis after digestion with XbaI. Lanes 1–13, serotype K1 isolates; lanes 14–16, serotype K2 isolates; lane 17, serotype non-K1/K2 isolates. M, molecular mass marker; P, liver aspirate; ST, stool; SA, saliva.
Figure 2
Figure 2
Pulsed-field gel electrophoresis of Klebsiella pneumoniae isolates from fecal samples of 7 patient groups with liver abscess and healthy carriers, Taiwan, January 2009–December 2010. G, patient group; M, molecular mass marker; P, patient; HC, healthy carrier.
See this image and copyright information in PMC

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