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. 2012 Aug;18(8):1225-34.
doi: 10.3201/eid1808.111355.

Vaccination of health care workers to protect patients at increased risk for acute respiratory disease

Gayle P Dolan  1 , Rebecca C Harris, Mandy Clarkson, Rachel Sokal, Gemma Morgan, Mitsuru Mukaigawara, Hiroshi Horiuchi, Rachel Hale, Laura Stormont, Laura Béchard-Evans, Yi-Sheng Chao, Sergey Eremin, Sara Martins, John S Tam, Javier Peñalver, Arina Zanuzdana, Jonathan S Nguyen-Van-Tam
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Vaccination of health care workers to protect patients at increased risk for acute respiratory disease

Gayle P Dolan et al. Emerg Infect Dis. 2012 Aug.

Erratum in

  • Emerg Infect Dis. 2013 Mar;19(3):523. Zanuzadana, Arina [corrected to Zanuzdana, Arina]

Abstract

Health care workers (HCWs) may transmit respiratory infection to patients. We assessed evidence for the effectiveness of vaccinating HCWs to provide indirect protection for patients at risk for severe or complicated disease after acute respiratory infection. We searched electronic health care databases and sources of gray literature by using a predefined strategy. Risk for bias was assessed by using validated tools, and results were synthesized by using a narrative approach. Seventeen of the 12,352 identified citations met the full inclusion criteria, and 3 additional articles were identified from reference or citation tracking. All considered influenza vaccination of HCWs, and most were conducted in long-term residential care settings. Consistency in the direction of effect was observed across several different outcome measures, suggesting a likely protective effect for patients in residential care settings. However, evidence was insufficient for us to confidently extrapolate this to other at-risk patient groups.

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Study selection for a review of the vaccination of health care workers to protect patients at risk for acute respiratory disease.
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