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Comment
. 2012 Jul 27;47(2):153-5.
doi: 10.1016/j.molcel.2012.07.007.

Should I stay or should I go? Chromodomain proteins seal the fate of heterochromatic transcripts in fission yeast

Kevin M Creamer  1 , Janet F Partridge
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Should I stay or should I go? Chromodomain proteins seal the fate of heterochromatic transcripts in fission yeast

Kevin M Creamer et al. Mol Cell. .
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Abstract

In this issue of Molecular Cell, Ishida et al. (2012) and Keller et al. (2012) show distinct outcomes for heterochromatic RNAs that bind different chromodomain proteins; Chp1 tethers transcripts to centromeres, whereas Swi6(HP1)-bound transcripts are evicted from chromatin and destroyed.

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