Review
Clinical pharmacokinetic studies with lornoxicam
Affiliations
- PMID: 2284218
Item in Clipboard
Review
Clinical pharmacokinetic studies with lornoxicam
Postgrad Med J.
1990.
Abstract
Pharmacokinetic data from several studies in young and elderly human subjects are reviewed. Lornoxicam appears to be extensively metabolized and no unchanged drug has been found in the urine. It has a relatively short elimination half-life (about 4 hours), and no significant differences in pharmacokinetic data have been found between young and elderly volunteers.
Similar articles
-
Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents.Clin Pharmacokinet. 1994 Feb;26(2):107-20. doi: 10.2165/00003088-199426020-00004. Clin Pharmacokinet. 1994. PMID: 8162655 Review.
-
Clinical pharmacokinetics of lornoxicam. A short half-life oxicam.Clin Pharmacokinet. 1998 Jun;34(6):421-8. doi: 10.2165/00003088-199834060-00001. Clin Pharmacokinet. 1998. PMID: 9646006 Review.
-
Pharmacokinetics of lornoxicam in man.Postgrad Med J. 1990;66 Suppl 4:S22-7. Postgrad Med J. 1990. PMID: 2284217 Clinical Trial.
-
Chlortenoxicam pharmacokinetics in young and elderly human volunteers.Postgrad Med J. 1988 Oct;64(756):752-4. doi: 10.1136/pgmj.64.756.752. Postgrad Med J. 1988. PMID: 3255915 Free PMC article. Clinical Trial.
-
Pharmacokinetics of piroxicam: new aspects.Eur J Rheumatol Inflamm. 1987;8(1):42-8. Eur J Rheumatol Inflamm. 1987. PMID: 3622592
Cited by
-
Pharmacokinetics of oxicam nonsteroidal anti-inflammatory agents.Clin Pharmacokinet. 1994 Feb;26(2):107-20. doi: 10.2165/00003088-199426020-00004. Clin Pharmacokinet. 1994. PMID: 8162655 Review.
-
Lornoxicam pharmacokinetics in relation to cytochrome P450 2C9 genotype.Br J Clin Pharmacol. 2005 Jan;59(1):14-7. doi: 10.1111/j.1365-2125.2005.02223.x. Br J Clin Pharmacol. 2005. PMID: 15606435 Free PMC article. Clinical Trial.
-
Clinical pharmacokinetics of lornoxicam. A short half-life oxicam.Clin Pharmacokinet. 1998 Jun;34(6):421-8. doi: 10.2165/00003088-199834060-00001. Clin Pharmacokinet. 1998. PMID: 9646006 Review.
-
Role of human liver microsomal CYP2C9 in the biotransformation of lornoxicam.Eur J Clin Pharmacol. 1996;49(4):305-8. doi: 10.1007/BF00226332. Eur J Clin Pharmacol. 1996. PMID: 8857077
-
A pharmacokinetic interaction between cimetidine or ranitidine and lornoxicam.Postgrad Med J. 1993 Nov;69(817):865-6. doi: 10.1136/pgmj.69.817.865. Postgrad Med J. 1993. PMID: 8290432 Free PMC article. Clinical Trial.