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Multicenter Study
. 2012 Nov;36(11):2261-7.
doi: 10.1007/s00264-012-1623-5. Epub 2012 Jul 29.

Predictors for moderate to severe acute postoperative pain after total hip and knee replacement

Affiliations
Multicenter Study

Predictors for moderate to severe acute postoperative pain after total hip and knee replacement

Spencer S Liu et al. Int Orthop. 2012 Nov.

Abstract

Purpose: The ability to identify and focus care to patients at higher risk of moderate to severe postoperative pain should improve analgesia and patient satisfaction, and may affect reimbursement. We undertook this multi-centre cross-sectional study to identify preoperative risk factors for moderate to severe pain after total hip (THR) and knee (TKR) replacement.

Methods: A total of 897 patients were identified from electronic medical records. Preoperative information and anaesthetic technique was gained by retrospective chart review. The primary outcomes were moderate to severe pain (pain score ≥ 4/10) at rest and with activity on postoperative day one. Logistic regression was performed to identify predictors for moderate to severe pain.

Results: Moderate to severe pain was reported by 20 % at rest and 33 % with activity. Predictors for pain at rest were female gender (OR 1.10 with 95 % CI 1.01-1.20), younger age (0.96, 0.94-0.99), increased BMI (1.02, 1.01-1.03), TKR vs. THR (3.21, 2.73-3.78), increased severity of preoperative pain at the surgical site (1.15, 1.03-1.30), preoperative use of opioids (1.63, 1.32-2.01), and general anaesthesia (8.51, 2.13-33.98). Predictors for pain with activity were TKR vs. THR (1.42, 1.28-1.57), increased severity of preoperative pain at the surgical site (1.11, 1.04-1.19), general anaesthesia (9.02, 3.68-22.07), preoperative use of anti-convulsants (1.78, 1.32-2.40) and anti-depressants (1.50, 1.08-2.80), and prior surgery at the surgical site (1.28, 1.05-1.57).

Conclusions: Our findings provide clinical guidance for preoperative stratification of patients for more intensive management potentially including education, nursing staffing, and referral to specialised pain management.

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Figures

Fig. 1
Fig. 1
Histogram of distribution of postsurgical pain scores at rest on postoperative day 1
Fig. 2
Fig. 2
Histogram of distribution of postsurgical pain scores with activity on postoperative day 1

References

    1. Scholten W, Nygren-Krug H, Zucker HA. The World Health Organization paves the way for action to free people from the shackles of pain. Anesth Analg. 2007;105:1–4. doi: 10.1213/01.ane.0000267542.72315.34. - DOI - PubMed
    1. Lee A, Chan SK, Chen PP, Gin T, Lau AS, Chiu CH. The costs and benefits of extending the role of the acute pain service on clinical outcomes after major elective surgery. Anesth Analg. 2010;111:1042–1050. - PubMed
    1. Kurtz S, Ong K, Lau E, Mowat F, Halpern M. Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030. J Bone Joint Surg Am. 2007;89:780–785. doi: 10.2106/JBJS.F.00222. - DOI - PubMed
    1. Macfarlane AJ, Prasad GA, Chan VW, Brull R. Does regional anesthesia improve outcome after total knee arthroplasty? Clin Orthop Relat Res. 2009;467:2379–2402. doi: 10.1007/s11999-008-0666-9. - DOI - PMC - PubMed
    1. Macfarlane AJ, Prasad GA, Chan VW, Brull R. Does regional anaesthesia improve outcome after total hip arthroplasty? A systematic review. Br J Anaesth. 2009;103:335–345. doi: 10.1093/bja/aep208. - DOI - PubMed

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