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. 2012 Jul 15;4(7):181-3.
doi: 10.4251/wjgo.v4.i7.181.

Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature

Shweta Kurian  1 , Jessica Macintyre, Muzammil Mushtaq, Caio Max Rocha-Lima, Yeon Ahn
Affiliations

Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature

Shweta Kurian et al. World J Gastrointest Oncol. .

Abstract

Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.

Keywords: Disseminated intravascular coagulation; Hematological emergencies; Metastatic colon cancer; Oxaliplatin; Platelet count.

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