Obsessive compulsive symptoms in individuals at clinical risk for psychosis: association with depressive symptoms and suicidal ideation
- PMID: 22846651
- PMCID: PMC3423559
- DOI: 10.1016/j.schres.2012.07.009
Obsessive compulsive symptoms in individuals at clinical risk for psychosis: association with depressive symptoms and suicidal ideation
Abstract
Obsessive-compulsive symptoms, particularly aggressive obsessions, are prevalent in schizophrenia patients and associated with other symptom severity, suicidal ideation and functional impairment. In a psychosis-risk cohort, obsessive-compulsive diagnosis and symptoms were assessed in terms of prevalence and content, and for associations with clinical measures. Obsessive-compulsive symptoms were prevalent in the CHR cohort, as was suicidal ideation. The presence and severity of aggressive obsessions were associated with depression, suicidal ideation and social impairment. The high prevalence of aggressive obsessions and associated suicidal ideation in a clinical high risk cohort, and their relationship to depression, is relevant for risk assessment and treatment strategies.
Copyright © 2012 Elsevier B.V. All rights reserved.
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References
-
- Abramowitz JS, Franklin ME, Schwartz SA, Furr JM. Symptom presentation and outcome of cognitive-behavioral therapy for obsessive-compulsive disorder. J Consult Clin Psychol. 2003;71(6):1049–1057. - PubMed
-
- Addington J, Piskulic D, Marshall C. Psychosocial treatments for schizophrenia. Curr Dir Psychol Sci. 2010;19(4):260–263.
-
- Adlard S. An Analysis of Health Damaging Behaviours in Young People at High Risk of Psychosis. Royal Australian and New Zealand College of Psychiatrists, Melbourne. 1997
-
- Anholt GE, van Oppen P, Emmelkamp PMG, Cath DC, Smit JH, van Dyck R, van Balkom AJLM. Measuring obsessive-compulsive symptoms: Padual Inventory-Revised vs. Yale-Brown Obsessive Compulsive Scale. J Anxiety Disord. 2009;23(6):830–835. - PubMed
-
- Balci V, Sevincok L. Suicidal ideation in patients with obsessive-compulsive disorder. Psychiatry Res. 2010;175:104–108. - PubMed
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