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. 2012 Sep 14;48(71):8964-6.
doi: 10.1039/c2cc34238c. Epub 2012 Jul 31.

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

Ge Wu  1 , Jun Zhou, Min Zhang, Peng Hu, Weiping Su
Affiliations

Palladium-catalyzed direct arylation of benzoxazoles with unactivated simple arenes

Ge Wu et al. Chem Commun (Camb). .

Abstract

Using CuBr(2) as an additive, the Pd-catalyzed intermolecular C-H-C-H cross-coupling between benzoxazoles and unactivated simple arenes has been developed. This protocol provides a straightforward approach for the biological activity of 2-arylbenzoxazole derivatives.

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