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. 2012 Aug;18(8):CR518-522.
doi: 10.12659/msm.883273.

Clinical parameters for prediction of successful labor induction after application of intravaginal dinoprostone in nulliparous Chinese women

Lei Hou  1 , Yu Zhu, Xiaomin Ma, Jianing Li, Weiyuan Zhang
Affiliations

Clinical parameters for prediction of successful labor induction after application of intravaginal dinoprostone in nulliparous Chinese women

Lei Hou et al. Med Sci Monit. 2012 Aug.

Abstract

Background: The aim of this study was to compare the possible clinical parameters for prediction of successful labor induction in Chinese nulliparous women.

Material/methods: A retrospective, observational trial of labor induction was performed, using a single dose of 10 mg controlled-release dinoprostone for preinduction cervical ripening in 127 nulliparous women (gestational age 38-42 weeks, singleton cephalic presentation). The characteristics of the women with successful labor induction (defined as vaginal delivery achieved on the day of admission; n=80) and failed labor induction (n=47) were compared.

Results: The main differences observed between the groups were gravidity (P<0.05), induction-active labor interval (5.16±2.98 vs. 8.40±3.41; P<0.05) and birth weight (3421.11±368.14 vs. 3566.36±345.16; P<0.05). Logistic regression demonstrated that gravidity (P<0.05) and induction-active labor interval (P<0.05), but not Bishop score, were significant and independent contributing factors for successful labor induction. In the receiver operating characteristic curves for the prediction of successful labor induction, the best cut-off value for gravidity was 3 (95% confidence interval [CI] 0.64-0.83, P=0.000), and the best cut-off value for the induction-active labor interval was 7.96 (95%CI 0.66-0.85, P=0.000).

Conclusions: Less gravidity and shorter induction-active labor interval predict successful labor induction with reasonable accuracy.

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Figures

Figure 1
Figure 1
Receiver operating characteristic (ROC) curve for gravidity (area under the curve [AUC]=0.738, 95%CI 0.64–0.83; P=0.000).
Figure 2
Figure 2
Receiver operating characteristic (ROC) curve for induction-active labor interval (area under the curve [AUC]=0.753, 95%CI 0.66–0.85; P=0.000).
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References

    1. Lilford RJ, van Coeverden de Groot HA, et al. The relative risks of caesarean section (intrapartum and elective) and vaginal delivery: a detailed analysis to exclude the effects of medical disorders and other acute pre-existing physiological disturbances. Br J Obstet Gynaecol. 1990;97(10):883–92. - PubMed
    1. Ryding EL, Wijma K, Wijma B. Experiences of emergency cesarean section: A phenomenological study of 53 women. Birth. 1998;25(4):246–51. - PubMed
    1. Creedy DK, Shochet IM, Horsfall J. Childbirth and the development of acute trauma symptoms: incidence and contributing factors. Birth. 2000;27(2):104–11. - PubMed
    1. van Ham MA, van Dongen PW, Mulder J. Maternal consequences of caesarean section. A retrospective study of intraoperative and postoperative maternal complications of caesarean section during a 10-year period. Eur J Obstet Gynecol Reprod Biol. 1997;74(1):1–6. - PubMed
    1. Martin JA, Hamilton BE, Sutton PD, et al. Births: final data for 2002. Natl Vital Stat Rep. 2003;52(10):1–113. - PubMed