Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2012 Aug 14;109(33):13144-5.
doi: 10.1073/pnas.1210412109. Epub 2012 Jul 31.

Nitrate transport in salivary glands with implications for NO homeostasis

Jon O Lundberg  1
Affiliations
Comment

Nitrate transport in salivary glands with implications for NO homeostasis

Jon O Lundberg. Proc Natl Acad Sci U S A. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflict of interest statement: J.O.L. is a named coinventor on pending patent applications regarding the therapeutic uses of nitrate and nitrite salts.

Comment on

  • Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane.
    Qin L, Liu X, Sun Q, Fan Z, Xia D, Ding G, Ong HL, Adams D, Gahl WA, Zheng C, Qi S, Jin L, Zhang C, Gu L, He J, Deng D, Ambudkar IS, Wang S. Qin L, et al. Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13434-9. doi: 10.1073/pnas.1116633109. Epub 2012 Jul 9. Proc Natl Acad Sci U S A. 2012. PMID: 22778404 Free PMC article.

References

    1. Lundberg JO, Weitzberg E, Cole JA, Benjamin N. Nitrate, bacteria and human health. Nat Rev Microbiol. 2004;2:593–602. - PubMed
    1. Spiegelhalder B, Eisenbrand G, Preussmann R. Influence of dietary nitrate on nitrite content of human saliva: Possible relevance to in vivo formation of N-nitroso compounds. Food Cosmet Toxicol. 1976;14:545–548. - PubMed
    1. Lundberg JO, Govoni M. Inorganic nitrate is a possible source for systemic generation of nitric oxide. Free Radic Biol Med. 2004;37:395–400. - PubMed
    1. Qin L, et al. Sialin (SLC17A5) functions as a nitrate transporter in the plasma membrane. Proc Natl Acad Sci USA. 2012;109:13434–13439. - PMC - PubMed
    1. Lundberg JO, Weitzberg E, Gladwin MT. The nitrate-nitrite-nitric oxide pathway in physiology and therapeutics. Nat Rev Drug Discov. 2008;7:156–167. - PubMed

MeSH terms

LinkOut - more resources