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Comment
. 2012 Aug 14;109(33):13142-3.
doi: 10.1073/pnas.1210290109. Epub 2012 Jul 31.

Extrasynaptic site of action for γ-hydroxybutyrate

Affiliations
Comment

Extrasynaptic site of action for γ-hydroxybutyrate

S J Enna. Proc Natl Acad Sci U S A. .
No abstract available

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Conflict of interest statement

The author declares no conflict of interest.

Comment on

References

    1. Enna SJ, Williams M. Challenges in the search for drugs to treat central nervous system disorders. J Pharmacol Exp Ther. 2009;329:404–411. - PubMed
    1. Absalom N, et al. α4βδ GABAA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB) Proc Natl Acad Sci USA. 2012;109:13404–13409. - PMC - PubMed
    1. Snead OC, 3rd, Furner R, Liu CC. In vivo conversion of gamma-aminobutyric acid and 1,4-butanediol to gamma-hydroxybutyric acid in rat brain. Studies using stable isotopes. Biochem Pharmacol. 1989;38:4375–4380. - PubMed
    1. Benavides J, et al. High affinity binding sites for gamma-hydroxybutyric acid in rat brain. Life Sci. 1982;30:953–961. - PubMed
    1. Snead OC, 3rd, Liu CC. Gamma-hydroxybutyric acid binding sites in rat and human brain synaptosomal membranes. Biochem Pharmacol. 1984;33:2587–2590. - PubMed

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