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. 2011 Aug;73(4):284-6.
doi: 10.1007/s12262-011-0282-x. Epub 2011 Apr 30.

The role of mediastinoscopy for diagnosis of isolated mediastinal lymphadenopathy

Zubin M Nalladaru  1 , Andre Wessels
Affiliations

The role of mediastinoscopy for diagnosis of isolated mediastinal lymphadenopathy

Zubin M Nalladaru et al. Indian J Surg. 2011 Aug.

Abstract

To determine the role of mediastinoscopy (MDS) in the histological diagnosis of isolated mediastinal lymphadenopathy in a centre where more sophisticated investigations, like positron emitting tomography (PET) scan and endobronchial ultrasound guided trans-bronchial needle aspiration (EBUS-TBNA) is not available. This is a retrospective study. From January 2006 to December 2009, 31 patients with isolated mediastinal lymphadenopathy underwent MDS to establish a histological diagnosis. The mean age was 36.3 years. Among the patients, 19 were males and 12 were females. The most common symptom was dry cough in 18 (58%) patients. The diagnostic yield was 96.8%, with sarcoidosis being the commonest diagnosis. It was concluded that MDS was vital in establishing a histological diagnosis in patients with isolated mediastinal lymphadenopathy.

Keywords: Lymphadenpathy; Lymphoma; Mediastinoscopy; Sarcoidosis; Tuberculosis.

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References

    1. Carlens E. Mediastinoscopy: a method for inspection and tissue biopsy in the superior mediastinum. Dis Chest. 1959;36:343–349. - PubMed
    1. Lee BE, Redwine J, Foster C, Abella E, Lown T, Lau D, Follette D. Mediastinoscopy might not be necessary in patients with non–small cell lung cancer with mediastinal lymph nodes having a maximum standardized uptake value of less than 5.3. J Thorac Cardiovasc Surg. 2008;135:615–619. doi: 10.1016/j.jtcvs.2007.09.029. - DOI - PubMed
    1. Kirschner PA. Cervical mediastinoscopy. Chest Surg Clin N Am. 1996;6(1):1–20. - PubMed
    1. Ginsberg RJ. Extended cervical mediastinoscopy. Chest Surg Clin N Am. 1996;6:20–30. - PubMed
    1. Hammoud ZT, Anderson RC, Myers BF, Guthrie TJ, Roper CL, Cooper JD, Patterson GA. The current role of mediastinoscopy in the evaluation of thoracic disease. J Thorac Cardiovasc Surg. 1999;118:894–899. doi: 10.1016/S0022-5223(99)70059-0. - DOI - PubMed

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