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Clinical Trial
. 1990 Sep;34(9):1803-5.
doi: 10.1128/AAC.34.9.1803.

Comparative study of cephradine and amoxicillin-clavulanate in the treatment of recurrent urinary tract infections

W Brumfitt  1 , J M Hamilton-Miller
Affiliations
Clinical Trial

Comparative study of cephradine and amoxicillin-clavulanate in the treatment of recurrent urinary tract infections

W Brumfitt et al. Antimicrob Agents Chemother. 1990 Sep.

Abstract

Eighty-eight female patients with a history of recurrent urinary tract infections were treated according to a randomization scheme with either 1 g of cephradine every 12 h (47 patients) or 375 mg of amoxicillin-clavulanate every 8 h (41 patients) for 7 days. The treatments were equally effective (cure rates of 89% for cephradine and 88% for amoxicillin-clavulanate) and showed similar relapse rates (cephradine, 14%; amoxicillin-clavulanate, 11%). Adverse effects were similar in both groups (cephradine, 23%; amoxicillin-clavulanate, 22%).

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