Cutaneous metastases of internal tumors

Abstract

Cutaneous metastases are relatively rare in clinical practice and their diagnosis requires a high index of suspicion because clinical findings can be subtle. These metastases reveal the presence of disseminated malignant disease and can lead to the diagnosis of unsuspected internal tumors or the spread or recurrence of an already diagnosed tumor. Early recognition of cutaneous metastases can facilitate prompt and accurate diagnosis resulting in early treatment; however, they are generally indicative of a poor prognosis. Some tumors have a predilection to metastasize to specific areas. Recognition of these patterns provides essential information that can guide the search for the underlying tumor.

Keywords: Cascada metastásica; Cutaneous metastases; Diseminación; Dissemination; Immunohistochemistry; Inmunohistoquímica; Metastatic cascade; Metastatic pattern; Metástasis cutáneas; Nodule; Nódulo; Patrones metastásicos.