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Case Reports
. 2012 Oct;31(10):500-4.
doi: 10.5732/cjc.012.10118. Epub 2012 Aug 2.

Metaplastic carcinoma of the right breast and simultaneous giant ovarian teratoma: a case report

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Case Reports

Metaplastic carcinoma of the right breast and simultaneous giant ovarian teratoma: a case report

Shuang Li et al. Chin J Cancer. 2012 Oct.

Abstract

We describe here a female patient who presented with a breast mass and giant abdominal mass. Fine needle aspiration cytology of the breast mass and histological examination after modified radical mastectomy confirmed metaplastic carcinoma of the breast. The epithelial components were formed by infiltrating ductal carcinoma with poor differentiation, and the sarcomatous components were formed by fibrosarcoma and osteosarcoma. Histological examination of the abdominal mass confirmed ovarian teratoma. The patient underwent modified radical mastectomy of the right breast and laparoscopic excision of the abdominal mass in the lower right quadrant. Having underwent six courses of chemotherapy, the patient is now in her tenth month after surgery and under follow-up, and she has no relapsed disease. These two diseases have never seen in one patient before. The case we report here provides some new data for research and clinical experience and it may also provide a new insight into the relationship between metaplastic breast carcinoma and ovarian teratoma.

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Figures

Figure 1.
Figure 1.. Histological examinations of the right breast tumor.
A, epithelial and mesenchymal components of carcinosarcoma are shown together and cancer nests are observed (HE ×40); B, the bone matrix can be seen among allotypic cells (HE ×200); C, allotypic cells are apparent (HE ×400).
Figure 2.
Figure 2.. The histological image of the ovarian teratoma.
The tumor is consisted of diverse mature tissues, including skin and cutaneous appendages (HE ×40).
Figure 3.
Figure 3.. Immunohistochemistry of the right breast tumor.
The myoepithelial cells around the cancer nest disappeared. Cytokeratin 5/6 (CK5/6) and smooth muscle actin (SMA) are negative in the tumor (HE ×40).

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References

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