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Randomized Controlled Trial
. 2012 Nov;91(11):951-6.
doi: 10.1097/PHM.0b013e31826458c6.

Relationship between body mass index and rehabilitation outcomes in chronic stroke

Lynne R Sheffler  1 , Jayme S Knutson, Douglas Gunzler, John Chae
Affiliations
Randomized Controlled Trial

Relationship between body mass index and rehabilitation outcomes in chronic stroke

Lynne R Sheffler et al. Am J Phys Med Rehabil. 2012 Nov.

Abstract

Objective: The aim of this study was to evaluate the relationship between body mass index (BMI) and change in motor impairment and functional mobility after a gait rehabilitation intervention in chronic stroke subjects.

Design: Correlation and linear regression analyses of pretreatment and end-of-treatment Fugl-Meyer scores and modified Emory Functional Ambulation Profile scores from hemiparetic subjects (n = 108, >3 mos post stroke) who participated in a randomized controlled trial comparing two 12-wk ambulation training treatments were generated.

Results: A series of linear regression models that controlled for age, sex, stroke type, interval post-stroke, and training device found the change in the Fugl-Meyer score to be significantly negatively associated with pretreatment BMI (β = -0.207, P = 0.036) and the change in the "up and go" modified Emory Functional Ambulation Profile score to be significantly positively associated with BMI (β = 0.216, P = 0.03). Changes in modified Emory Functional Ambulation Profile scores in floor, carpet, obstacles, or stair climbing were not significantly associated with BMI.

Conclusions: Chronic stroke subjects with a higher BMI were less likely to demonstrate improvement in motor impairment and up and go functional mobility performance in response to ambulation training, irrespective of treatment intervention. Stroke rehabilitation clinicians should consider BMI when formulating rehabilitation goals. Further studies are necessary to determine whether obesity is a predictor of longer-term post-stroke motor and functional recovery.

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Conflict of interest statement

Disclosures:

Financial disclosure statements have been obtained, and no conflicts of interest have been reported by the authors or by any individuals in control of the content of�this article.

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References

    1. Strazzullo P, D'Elia L, Cairella G, Garbagnati F, Cappuccio FP, Scalfi L. Excess body weight and incidence of stroke: meta-analysis of prospective studies with 2 million participants. Stroke. 2010;41:e418–e426. - PubMed
    1. Salihu HM, Bonnema SM, Alio AP. Obesity: What is an elderly population growing into? Maturitas. 2009;63:7–12. - PubMed
    1. Mascitelli L, Pezzetta F, Goldstein MR. Body mass index, cholesterol level and poststroke mortality. Neuroepidemiology. 2008;31:138. author reply. - PubMed
    1. Alley DE, Chang VW. The changing relationship of obesity and disability, 1988–2004. JAMA. 2007;298:2020–2027. - PubMed
    1. Apovian CM, Frey CM, Wood GC, Rogers JZ, Still CD, Jensen GL. Body mass index and physical function in older women. Obes Res. 2002;10:740–747. - PubMed

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