Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2011 Aug 17;2(8):381.
doi: 10.1021/cn200061g. Epub 2011 Jul 6.

ACS chemical neuroscience molecule spotlight on STX209 (arbaclofen)

Affiliations
Review

ACS chemical neuroscience molecule spotlight on STX209 (arbaclofen)

Corey R Hopkins. ACS Chem Neurosci. .

Abstract

STX209 (arbaclofen) is a γ-amino butyric acid type B (GABA(B)) receptor agonist from Seaside Therapeutics currently in clinical trials for autism spectrum disorders (ASD). The company has initiated a phase 2b study after positive results from a phase 2a trial, announced September 2010 (http://www.seasidetherapeutics.com/sites/default/files/STX209_ASD_P2b Trial_Initiation%206%2021%202011%20Final.pdf).

Keywords: GABA; STX209; autism spectrum disorder (ASD).

PubMed Disclaimer

Similar articles

Cited by

References

    1. http://www.cdc.gov/ncbddd/autism/facts.html.
    1. Healy A., Rush R., and Ocain T. (2011) Fragile X syndrome: an udpate on developing treatment modalities. ACS Chem. Neurosci. published online March 22, 2011. DOI: 10.1021/cn200019z. - DOI - PMC - PubMed
    1. Emmitte K. A. (2011) Recent advances in the design and development of novel negative allosteric modulators of mGlu5. ACS Chem. Neurosci. published online April 15, 2011. DOI: 10.1021/cn2000266. - DOI - PMC - PubMed
    1. http://www.seasidetherapeutics.com/sites/default/files/news_media-releas....

MeSH terms