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Review
. 2011 Aug 17;2(8):381.
doi: 10.1021/cn200061g. Epub 2011 Jul 6.

ACS chemical neuroscience molecule spotlight on STX209 (arbaclofen)

Corey R Hopkins  1
Affiliations
Review

ACS chemical neuroscience molecule spotlight on STX209 (arbaclofen)

Corey R Hopkins. ACS Chem Neurosci. .

Abstract

STX209 (arbaclofen) is a γ-amino butyric acid type B (GABA(B)) receptor agonist from Seaside Therapeutics currently in clinical trials for autism spectrum disorders (ASD). The company has initiated a phase 2b study after positive results from a phase 2a trial, announced September 2010 (http://www.seasidetherapeutics.com/sites/default/files/STX209_ASD_P2b Trial_Initiation%206%2021%202011%20Final.pdf).

Keywords: GABA; STX209; autism spectrum disorder (ASD).

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References

    1. http://www.cdc.gov/ncbddd/autism/facts.html.
    1. Healy A., Rush R., and Ocain T. (2011) Fragile X syndrome: an udpate on developing treatment modalities. ACS Chem. Neurosci. published online March 22, 2011. DOI: 10.1021/cn200019z. - DOI - PMC - PubMed
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    1. http://www.seasidetherapeutics.com/sites/default/files/news_media-releas....

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